When it comes to choosing a probiotic for your baby, the options can feel overwhelming. Not all probiotics are the same, and different strains have been studied for different concerns—from colic and digestion to immune support.
Rather than focusing on marketing claims, it can be helpful to look at products that are commonly used in clinical practice and have some evidence behind them. Below are a few options to consider, depending on your baby’s needs.
Infant Probiotic Options
When I’m choosing probiotics for babies, I’m looking for products that are evidence-informed and practical for parents to actually use. Here are the ones I reach for most often in practice:
Best Probiotic Drops for Colic and Digestion
BioGaia Protectis Baby Drops

These drops contain Lactobacillus reuteri DSM 17938, one of the most well-studied probiotic strains for infants.
This strain has been researched for colic, constipation, and regurgitation—common concerns in early infancy. The liquid format makes it easy to use: it can be given directly, mixed into formula, or applied before feeding.
Where to find it:
Best Infant Probiotic for Diarrhea and Immune Support
Metagenics UltraFlora Baby

This formula combines Lactobacillus rhamnosus GG (LGG) and Bifidobacterium lactis (BB-12), two of the most widely studied probiotic strains in infants.
These strains have been researched for diarrhea (including antibiotic-associated diarrhea), colic, and immune support. The liquid format makes it easy to administer consistently.
Where to find it:
Best Multi-Strain Probiotic for Infants
Genestra HMF Baby Line

This line includes several options (HMF Baby B, HMF Baby F, HMF Baby Immune, and drops), allowing for more tailored support depending on your baby’s needs.
These products combine multiple probiotic strains and come in both powder and liquid formats. Powders can be mixed into breastmilk, formula, or soft foods.
Dr. Domenique adds: Multi-strain probiotics can be helpful when you’re looking for broader digestive and immune support, especially when feeding method or health history varies.
Where to find it:
- U.S.: Limited availability
Dr. Dominique's Food-Based Probiotic Option for Infants
KefirKult Coconut Kefir

For families interested in food-based probiotics, this cultured coconut kefir offers a dairy-free source of live microorganisms.
It’s made without added fillers or flavours and can be introduced in small, age-appropriate amounts as part of a varied diet.
Dr. Domenique adds: Food-based probiotics can be a helpful complement to supplements when tolerated and introduced appropriately
Where to find it:
- Shop their website here
Probiotics for your infant
The “best” probiotic for your baby will always depend on the specific concern you’re trying to support, along with your baby’s age, feeding method, and overall health.
If you’re unsure where to start, working with a healthcare provider can help you choose a product and strain that makes sense for your child. And remember—probiotics can be helpful in certain situations, but they’re just one piece of the bigger picture when it comes to infant gut health.
Other articles you may like: Establishing the Infant Microbiome, What Your Infant's Poop Says about Their Health, and Can I Take Probiotics While Breastfeeding?